Sunday, January 30, 2011

Molybdenum cofactor biosynthesis protein MoaC.



The molybdenum cofactor (Moco) is an essential component of a large family of enzymes involved in important transformations in carbon, nitrogen and sulfur metabolism. The Moco biosynthetic pathway is evolutionarily conserved and found in archaea, eubacteria and eukaryotes. In humans, genetic deficiencies of enzymes involved in thispathway trigger an autosomal recessive and usually deadly disease with severe neurological symptoms. The MoaC protein,together with the MoaA protein, is involved in the first step of Moco biosynthesis. (from paper abstract)
Wuebbens et al. Structure Fold.Des. 8: 709-717

12 comments:

  1. Enzymes have got to be some of the most amazing things in nature. They are, in many respects, nano-sized machines. They show down to the molecular level just how highly coordinated and mind-bogglingly complex the systems in our bodies are, and yet confirm they are a product of, and vassal to, the basic laws of chemistry and physics. The fact that they are so tuned to their jobs is also amazing: a single atom of the metal molybdenum is required for this enzyme to operate, and nothing else will do. Incredible.

    ReplyDelete
  2. It is no secret that I have a very deep and personal relationship with God. I have pushed and resisted that relationship this past year through all the bullshit I have had to go through living with Herpes but once again, God is bigger than my stubbornness and broke through that outbreak cold sore and all I had Genital Herpes. For me personally, hearing over and over how I am not good enough has really invaded my mind in the worst way possible. I completely shut down and I was just waking up like is this how life going to end this temporary herpes outbreak “fuck everybody with herpes if you know what I mean” but let's be honest here...
    It is a cowardly to say no to herbal medicine. It is fear based. And it is dishonest to what my heart wants. Don't build a wall around yourself because you are afraid of herbals made or taking a bold step especially when it's come to health issues and getting cure. So many young men/ women tell me over and over that Dr Itua is going to scam me but I give him a try to today I feel like no one will ever convince me about herbal medicine I accept Dr Itua herbal medicine because it's cure my herpes just two weeks of drinking it and i have been living for a year and months now I experience outbreak no more, You can contact him if you need his herbal medicine for any such diseases like, Herpes, Schizophrenia,Cancer,Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity Syndrome Fibrodysplasia Ossificans Progressiva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic,Diabetes ,Coeliac disease,Creutzfeldt–Jakob,,Lyme Disease,Epilepsy, ,ALS,Hepatitis,Copd,Parkinson disease.Genetic disease,Fibrodysplasia disease,Fibrodysplasia Ossificans Men/Woman infertility, bowel disease ,Huntington's disease ,Diabetes,Fibroid. disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Sclerosis,Alzheimer's disease,Adrenocortical carcinoma.Asthma,Allergic,HIV, Epilepsy, Infertility, Love Spell,. Email..drituaherbalcenter@gmail.com then what's app.+2348149277967.... My advice to any sick men/women out there is simple... Be Always an open book. Be gut wrenching honest about yourself, your situation, and what you are all about. Don't hold anything back. Holding back will get you nowhere...maybe a one way ticket to lonelyville and that is NOT somewhere you want to be. So my final truth...and I'm just starting to grasp this one..

    ReplyDelete
  3. This is very interesting. thanks for that. we need more sites like this. i commend you on your great content and excellent topic choices. written codes of ethics for health care practitioners

    ReplyDelete
  4. Good day to all am  From USA..Texas am so happy sharing this great testimony on here, I was diagnose of Stage IV colon cancer.i was checking for solution in the internet then miraculously i came Across Dr Itua herbal center the powerful herbal doctor that Cure Numerous Diseases such as-Thyroid Cancer,Uterine cancer,Fibroid,Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Sclerosis,Brain Tumor,Fibromyalgia,Fluoroquinolone ToxicityBladder cancer,Brain cancer,Hiv,Herpes,Esophageal cancer,Gallbladder cancer,Gestational trophoblastic disease,Head and neck cancer,Hodgkin lymphoma
    Intestinal cancer,Kidney cancer,Hpv,Lung cancer,Melanoma,Mesothelioma,Multiple myeloma,Neuroendocrine tumors
    Non-Hodgkin lymphoma,Oral cancer,Ovarian cancer,Sinus cancer,Hepatitis A,B/C,Skin cancer,Soft tissue sarcoma,Pancreatic Cancer,Spinal cancer,Stomach cancer,Vaginal cancer,Vulvar cancer,
    Testicular cancer,Tach Diseases,Leukemia,Liver cancer,Throat cancer,
    Syndrome Fibrodysplasia Ossificans ProgresS sclerosis,Alzheimer's disease,Chronic Diarrhea,Copd,Parkinson,Als,Adrenocortical carcinoma  Infectious mononucleosis. ,I contacted him based on the testimonies I?m seeing about him on the internet, I was cured too by him, kindly contact him today through his email he can help you.     drituaherbalcenter@gmail.com  web and his herbal medicines will set you free from any human diseases,all thank you Dr Itua herbal center for your kind help in my life. His Mobile number Whatsapp.+2348149277967.

    ReplyDelete
  5. Youre so cool! I dont suppose Ive read anything like this before. So nice to search out any individual with some original thoughts on this subject. realy thank you for starting this up. this website is one thing that’s wanted on the web, somebody with a bit of originality. useful job for bringing something new to the internet! original largo cream price in pakistan

    ReplyDelete
  6. Denture largo cream use in urdu
    are adhesives that hold the dentures to the gums. However, they pose certain dangers to people who are allergic to them. Find out more in this article.

    ReplyDelete
  7. 'What is really in our ice cream' largo cream side effects the closed doors of mass market manufacturers of ice creams and how they make huge profits from inflating their produce with air, water and chemicals. When is whipped palm oil described as ice cream, what colours and additives are put in and why should one look to source locally made ice cream from artisan producers are all considered here.

    ReplyDelete
  8. Did you know that you most likely live within a short distance of cheaper prescription medicine than you are now paying? If you are having to choose between filling your prescription or buying food for viagra tablet side effects may want to read on. This article will not only explain how you can save thousands of dollars in prescription medicine but also where you can get it for a lot less.

    ReplyDelete
  9. Common coursework in Oriental medicine colleges entails studies in Chinese medical theory, bioscience,pfizer viagra price in pakistan herbal medicine and nutrition. In addition, practical training in acupuncture, moxibustion, cupping, Tai Chi, Qigong, and other related TCM (traditional Chinese medicine) healing techniques and treatments are included in educational programs at Oriental medicine colleges today.

    ReplyDelete
  10. Holistic largo cream results is a system of health care which fosters a cooperative relationship among all those involved, leading towards optimal attainment of the physical, mental, emotional, social and spiritual aspects of health. Holistic medicine is a term used to describe therapies that attempt to treat the patient as a whole person. Holistic Medicine is based on the core belief that unconditional love is life's most powerful healer.

    ReplyDelete
  11. Learn the truth about amazing arthritis medicine. Does it deliver as promised? medicalstoreonline.pk/product/vigrx-plus-price-in-pakistan/

    ReplyDelete
  12. Tired of allopathic treatments and looking for another way? Then herbal medicines could be the apt choice. Herbal medicines were used in ancient periods by our ancestors to heal diseases. www.medicalstoreonline.pk/product/viagra-price-in-pakistan/

    ReplyDelete